Tamoxifen citrate (Nolvadex)

Tamoxifen citrate is a selective estrogen receptor modulator (SERM), which was created in 1961 by the pharmacological company ICI, under the trademark AstraZenaca. Today, there is a large number of universal forms of Tamoxifen Citrate in the consumer market, but the most famous of them is Nolvadex. Very often Tamoxifen citrate is called anti-estrogen, although its positive functions do not end there. Its most important feature is to act simultaneously in some parts of the body as an anti-estrogen, and in others as an estrogen.

For many decades, this drug has been very actively used in medical practice, namely in the treatment of breast cancer. He is equally popular with consumers of anabolic steroids, although Tamoxifen citrate does not belong to the category of anabolic. The fact that this drug helps fight the manifestation of side effects of estrogenic nature, which are inherent in most anabolic steroids. Very often it is used as part of post-course therapy with PCT. Start PCT is necessary in 3 – 6 weeks after the end of reception of anabolic steroids. This therapy helps significantly speed up the process of restoring the natural production of testosterone, which was suppressed during the intake of hormonal anabolics.

Distinctive features and main functions Tamoxifen citrate

The fact is that Tamoxifen citrate is a drug of the SERM category, which can simultaneously act as an anti-estrogen and estrogen in different parts of the body. As an anti-estrogen drug is able to actively block the hormone estrogen. This fact is very important for patients with breast cancer, because often a malignant tumor eats precisely this hormone. Blocking levels of estrogen is of great importance for lovers of beautiful relief, because the increase in the level of this hormone is adversely affected by muscle tissue and can lead to gynecomastia.

For many users of Tamoxifen Citrate, this drug is not fully understood, because its ability to act simultaneously as an estrogen and anti-estrogen is indeed very surprising. As estrogen Tamoxifen citrate acts in the liver. It strengthens the cardiovascular system of a person and improves the cholesterol balance. This fact is very important for most users of anabolic steroids, because most of these drugs have a negative effect on your cholesterol balance. 

Also the use of Tamoxifen Citrate stimulates the pituitary gland and activates the production of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).

The positive effects of taking tamoxifen Citrate

For users of anabolic steroids, the positive effects of taking Tamoxifen Citrate are mainly to include this drug in PCT. It should be noted that such anabolic steroids as Testosterone and Nandrolone significantly increase the level of estrogen in the body. This is due to the conversion of testosterone to estrogen due to its interaction with the aromatase enzyme. The process of aromatization often leads to the appearance of such side effects as the retention of excess fluid in the body and gynecomastia. Over time, this can lead to high blood pressure. Tamoxifen citrate does not reduce estrogen levels in the body, but interacts directly with estrogen receptors and interferes with the activity of this hormone. It should be noted that this can not be a 100% guarantee of protection against gynecomastia for all men. A very big role in this matter is played by the genetic nature of man. If citrate tamoxifen does not provide the necessary protection, you need stronger drugs, and it’s better to start taking aromatase inhibitors (AI’s). Preparations of the AI’s category are anti-estrogens that block the action of aromatase and significantly reduce estrogen levels.

The most important feature of this drug for fans of anabolic steroids is its ability to activate testosterone production. The fact is that during the reception of anabolic steroids, the natural production of this hormone will definitely be suppressed. That is why almost all courses of hormonal anabolics have an additional testosterone in their composition. Once your cycle has come to an end, appropriate measures must be taken to resume the process of natural production of testosterone. Recovery may occur on its own, but this will take a lot of time, and taking Tamoxifen Citrate will greatly accelerate this process.


It is very important to note that any PCT that includes tamoxifen citrate or any SERM will help you only if before you started taking anabolic steroids you did not have any problems with the natural production of testosterone. 

Also, do not forget that many consumers of anabolic steroids are greatly mistaken when they think that a well-designed post-course therapy will contribute to a complete recovery of the body. In fact, Tamoxifen citrate will contribute to the recovery process, but it will not finish it. It takes several months to complete this process, but taking PCT will help you to survive this period more comfortably.

For patients with breast cancer, the positive effects of tamoxifen citrate are even more unambiguous than for users of anabolic steroids. The hormone estrogen actively feeds a malignant tumor, and Tamoxifen citrate blocks its activity and does not allow the tumor to grow. It should be noted that this is not the only one, but one of the most effective drugs in this direction. Usually, treatment starts with AI drugs and gradually switches to such a SERM as Tamoxifen Citrate. It is also often prescribed for the prevention of those women who have a very strong genetic predisposition to the manifestation of this disease.

Side Effects Tamoxifen Citrate


Indeed, while taking Tamoxifen Citrate, some negative side effects may appear, but it should be noted that this is one of the safest SERM’s products of those that exist today in the consumer market. Most men tolerate this drug very well and do not experience any negative symptoms. Side effects are more common during the administration of Tamoxifen Citrate by women. Typically, they include:

  • Vaginal Itching
  • Bleeding
  • Increased sweating
  • Stomach upset
  • Headache

It should be noted that the above side effects are possible, but in practice make themselves felt extremely rarely. Less common side effects that can occur during citrate Tamoxifen include the following manifestations:

  • Rash
  • Reducing the body’s leukocytes
  • Endometrial changes
  • Increase in triglyceride level
  • Pulmonary embolism

It is very important to note that this drug is banned for use by pregnant women and women who are preparing to conceive a child. The fact is that taking Tamoxifen Citrate or any other drug of the SERM category can greatly damage the developing embryo.

Dosage Tamoxifen Citrate


If we talk about therapeutic practice, in particular about the treatment of breast cancer, then there are 6 most common courses. Their average dosage is 10 to 20 milligrams of active ingredient per day. The amount of the drug should be divided into two doses. The duration of the course is individual and depends on the clinical picture. As a rule, Tamoxifen citrate is taken until the malignant tumor finally recedes, but after the treatment the drug intake is not stopped and taken for prevention and prevention of relapse.



If we talk about taking the drug for sport, then to protect against side effects of estrogenic nature, in particular from gynecomastia, the average dosage is 10-20 milligrams of active substance per day. If this dosage can not protect you from the estrogenic activity of anabolic steroids, it makes no sense to increase it, you just need to stop taking the drug and replace it with AI’s drugs. Many men are afraid to take AI’s drugs, as they prevent a significant increase in volume due to fluid retention in the body. However, you must clearly understand that excess water has nothing to do with muscle relief and is extremely undesirable in your body.

If we talk about post-course therapy, the initial dosage will be 40 milligrams of the active substance. The average course duration is 2 – 3 weeks. Then the dosage is reduced to 20 milligrams and continue to take the drug for 2 to 3 more weeks. In order for PCT to give a positive result, it is better to include several drugs in it. It is recommended in addition to citrate Tamoxifen to include in its course such a SERM as Clomiphene Citrate (Clomid).